They are either self-referred or sent in by their health care provider. S3 Table Methodological quality of included studies. Data extracted from each retrieved article included: At three months of age, There may have been an element of recall bias, especially for the women whose babies were admitted to hospital more than three years previously. Characteristics of voluntary participants versus nonparticipants in a psychoeducation program for euthymic patients with bipolar disorder. Conceived and designed the experiments:

Please review our privacy policy. Neonatal jaundice is one of the most common medical problems in healthy full-term infants during the immediate postnatal period 9. Comparison of seven methods. Assessment of the methodological qualities of the included studies is presented in S3 Table. Notwithstanding, the clinical risk factors reported in this study are consistent with findings in several studies that have investigated the causes of severe neonatal hyperbilirubinemia in LMICs and thus warrant attention. Press to Select an action Download. Discussion For the first time, there is a growing recognition among leading policy research groups such as the Child Health Epidemiology Reference Group CHERG of the World Health Organization WHO and the Global Burden of Disease Collaborators of the clinical and public health significance of hyperbilirubinemia in newborns as an important neonatal condition that deserves global health attention in the post millennium development goals era [ 35 , 36 ].

Length of breastfeeding and formula introduction were not found to be affected by return to work during the first year of life, despite previous reports clearly identifying early return to work 18 and full-time employment 19 as risk factors for breastfeeding discontinuation.

J Pediatric Neurology 9: Our eligibility criteria for studies on risk factors from eligible countries included cohort, cross-sectional or case-control studies with well-defined control groups and statistical adjustment for confounders. A randomized clinical trial.


thesis on neonatal hyperbilirubinemia

The education level was quite high, with most women having completed a university degree. Patients were eligible for the study based on the following criteria: Curr Opin Pediatr ; Please review our privacy policy.

Pediatrics Suppl 1: Three studies from Nigeria [ 11 ], India [ 24 ] and Pakistan [ 22 ] examined the role of G6PD deficiency on the risk of neonatal hyperbilirubinemia.

The impact of jaundice in newborn infants on the length of breastfeeding

Effects of fenofibrate treatment on cardiovascular disease risk in 9, individuals with type 2 diabetes and various components of the metabolic syndrome: A total of eleven risk factors were reported in two or more studies and included in the meta-analysis Table 3 and Fig. Trop Med Int Oh Arch Iran Med ; Comparison between duration of stay at hospital among the studied group Click here to view.

Given the nature of the study, the authors could not determine what kind of education, if any, mothers received with regard to breastfeeding and jaundice.

National Center for Biotechnology InformationU. Breastfeeding confers many advantages to infants, mothers, families and society in general 1.

thesis on neonatal hyperbilirubinemia

Perinatal and neonatal factors include gender [ 32 ], birth asphyxia [ 23 ], multiple gestation [ 26 ], severe anemia [ 29 ], acidosis [ 19 ], low birth weight [ 32 ], hypothermia [ 22 ], free bilirubin [ 23 ], and serum aflatoxin [ 21 ]. Clinical Guide to Laboratory Tests. Infants admitted with jaundice present to the emergency department. Scrafford, [ 32 ] May —Jan Bull World Health Organ S2 Table Quality assessment checklist for selected studies.

thesis on neonatal hyperbilirubinemia

New Ballard Score, expanded to include extremely premature infants. Two-sided confidence intervals for the single proportion: Thseis was adopted from a validated protocol for evaluating observational and non-randomized studies [ 18 ]. Table 1 Characteristics of included studies in the data syntheses.


The impact of jaundice in newborn infants on the length of breastfeeding

It is reasonable to postulate that if our study population were to have a level of education similar to that of the Infant Care Survey, our breastfeeding rates would have been lower. Maternal age, Ethnicity, Marital status, Parity Hyperbiliubinemia, Social class, House ownership and type, Antenatal care, Gestational age, Attendants at birth, Mode of delivery, Cord cutting, Delayed cry at birth, Hospitalization in the first 28 days.

Firstly, the meta-analysis neonayal based on data drawn from only five countries which may affect the generalizability of some of the findings to other eligible LMICs.

Patients neonatall excluded if they were exclusively formula-fed, had hyperbilirubinemia of the neonaatl conjugated type, had anatomical abnormalities such as cleft lip or palate potentially interfering with breastfeeding, were neurologically impaired, or were fed via nasogastric, nasojejunal or gastric tube.

A greater percentage of infants who received PT were small for gestational age, born in hospital 2, and bottle-fed. Breastfeeding rates at three and six months were not different between the study group and those reported in the Infant Care Survey Mail and Internet Surveys: As mentioned above, there may also have been selection bias, with more educated women being more likely to participate in the study.

There were wide variations in the primary outcomes, diagnostic criteria and putative risk factors explored across studies.